NCT06224205 · RECRUITING
Digital Detection of Dementia (D Cubed) Studies: D3
This trial is testing whether two digital screening tools — a Passive Digital Marker that analyzes existing health record data, and a caregiver-reported symptom questionnaire — can help primary care doctors catch Alzheimer's and related dementias earlier and more often. It is a pragmatic trial, meaning it is testing how well these tools work in real-world clinical settings, not a controlled lab environment. Details on the specific tools are somewhat limited in the source.
You may qualify if
- 65 years or older
- At least one visit to primary care practice within the past year
- Ability to provide informed consent
- Ability to communicate in English or Spanish
- Available EHR data from at least the past three years
You're excluded if
- Prior ADRD or mild cognitive impairment diagnosis as determined by ICD-10 code
- Evidence of any history of prescription for a cholinesterase inhibitors or memantine.
- Has serious mental illness such as bipolar or schizophrenia as determined by ICD-10 code
- Permanent resident of a nursing facility
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-10-27