NCT06114914 · UNKNOWN
TapTalkTest Project:Development of a Non-invasive Screening Test to Detect Risk of Alzheimer's Disease Pathology
This project is developing a smartphone-based screening test called TapTalk that analyzes hand movements and speech patterns to detect early signs of Alzheimer's-related brain changes. Participants tap and talk into their phone, and machine-learning algorithms look for patterns linked to Alzheimer's pathology. This is a diagnostic tool development study, not a treatment trial — the goal is to see whether this test can flag risk early, before symptoms appear.
Eligibility criteria
AIM 1 AND AIM 2 Eligibility criteria Inclusion Criteria: * Adults >50 years old who are participants in the ISLAND Project and who have provided a blood sample and have normal cognition and no persistent (>3 months) cognitive symptoms will be eligible. Exclusion Criteria: * Impaired cognition, defined by a validated cut-off score >1.5 SD above the mean total errors adjusted for age and gender on the Paired Associates Learning sub-test of CANTAB. AIM 3 Eligibility criteria Inclusion Criteria: >3 months of persistent cognitive symptoms (patient- or family-reported) and >50 years old. Exclusion criteria: Acutely unwell, significant impairment of hand function, or known diagnosis of mild cognitive impairment (MCI) or dementia.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2023-11-14