NCT06088810 · RECRUITING

The Impact of Music Intervention on Sleep

This trial is testing a personalized music app called CoMPoSER, designed to play calming music at bedtime to help people living with dementia sleep better. Researchers are also measuring caregiver stress and well-being. It is a Phase NA pilot randomized controlled trial — meaning this is an early-stage test of whether the approach works and whether people find the app acceptable to use.

Eligibility criteria

Inclusion Criteria for persons living with dementia (PLWD):
* Age 60 and above
* Existing physician diagnosis of dementia or self-reported memory impairment and Clinical Dementia Rating Scale score of greater than 0.5,
* Score of >10 on the Insomnia Severity Index
* Stable dose of psychotropic medications
* Agreeing to wear an actiwatch for the duration of the study
PLWD Exclusion Criteria:
* Hearing impairment
* Planned transition to a residential or institutional care facility in 3 months
* Presence of extrapyramidal symptoms or acute sleep disruption
* Bed bound
* Living in an alternative home setting (such as Assisted Living Community)
Informal caregivers inclusion criteria:
* Age 18 and above.
* Providing at least 4 hours of daily care
* Living with PLWD
* Able to read and communicate in English

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-04-07

View full record on ClinicalTrials.gov

All APOE4 clinical trials