NCT06055322 · RECRUITING
Reducing Suicide Risk Among Aging Caregivers of Persons With AD/ADRD
This trial is testing whether a therapy program called Dialectical Behavior Therapy, adapted for older family caregivers, can reduce suicidal thoughts and emotional distress in people caring for someone with Alzheimer's or a related dementia. It is a Phase NA study, meaning this is a pilot or feasibility design — researchers are building and testing the approach, not yet comparing it to a large control group in a definitive way.
Eligibility criteria
Inclusion Criteria: * being age 50 and over (as most informal caregivers of persons with AD/ADRD are 50 or older; AARP, 2020; Chi et al., 2019) * being the primary informal caregiver * living with an AD/ADRD-diagnosed patient * being willing to be prodded for bloodspots * demonstrating English-fluency * endorsing a direct or indirect SI/suicide risk * Eligible individuals will score above clinical cutoffs for SI/suicide risk on at least 1 of 3 measures: the Suicide Behavior Questionnaire-R (SBQ-R; score > 6; Osman et al., 2002), Interpersonal Needs Question-naire (INQ; thwarted belonging score > 35; and perceived burden > 17; Mitchell et al., 2020) or the Geriatric De-pression Scale (GDS; score > 5 Heisel et al., 2005). Exclusion Criteria: • Participants with neurocognitive impairment will be excluded (a Mini-Mental State Exam score ≤ 23; Folstein et al., 1975; Kochhann et al., 2010)
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-05-11