NCT05956834 · ACTIVE NOT RECRUITING

A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes

This observational study is tracking motor symptoms in people diagnosed with Progressive Supranuclear Palsy (PSP) using two wearable sensor devices — PAMSys and LEGSys — that monitor movement and balance remotely over 12 months. It is not a treatment trial; no drug or therapy is being tested. The goal is to see whether these devices can reliably capture how PSP progresses from home, potentially building a monitoring toolkit for related conditions like FTD. Details beyond that are limited.

You may qualify if

  • Clinical diagnosis of possible or probable PSP as defined by the 2017 MDS criteria
  • Fluent in reading and speaking English and capable of providing informed consent based on the principal investigator's judgement
  • Able to walk 10 feet unassisted at the time of initial enrollment
  • Must have a caregiver or study partner who is willing and able to assist with all study-related procedures

You're excluded if

  • Any neurological, medical, or psychiatric condition that would preclude participation in study activities based on the investigator's judgment.
  • A history of frequent falls defined as more than 5 falls per month, or who require a walker to ambulate safely at baseline will not be eligible to participate in the study.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-01-21

View full record on ClinicalTrials.gov

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