NCT05950607 · RECRUITING
Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0
This trial tests a structured care program designed to help nursing home staff manage suspected infections in residents with dementia more carefully — using fewer antibiotics and avoiding unnecessary procedures. It is a pragmatic cluster trial, meaning whole facilities are randomized rather than individual patients. This is a Phase NA behavioral study, meaning it evaluates a care practice, not a drug or device. Details on the specific program components are limited in the source.
Eligibility criteria
Inclusion Criteria: 1. Age > 60 2. A diagnosis of dementia (any type) 3. Cognitive Functional Scale (CFS) > 1 4. NH length of stay >90 days The CFS score categorizes cognitive impairment status based on data in the electronic health record into: 1. None, 2. Mild, 3. Moderate, and 4. Severe (advanced). For the primary outcome, the analysis will be restricted to residents with a CFS score of 3 or 4. Exclusion Criteria: 1. Less than 60 years of age 2. Living in nursing home for less than 90 days 3. Does not have diagnosis of dementia 4. Does not meet CFS >1 score
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-01-06