NCT05820919 · RECRUITING

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

This trial is testing a structured staff-led program called LOCK — focused on light exposure, activity, and consistent routines — to improve sleep in nursing home residents who already have Alzheimer's disease or a related dementia. Researchers are measuring whether sleep quality actually improves and whether nursing home staff can keep the program running over time. This is a Phase NA study, meaning it is a real-world implementation test, not a standard drug-safety or efficacy phase.

You may qualify if

  • Nursing home residents aged >=50 years with an Alzheimer disease or related dementia (ADRD) diagnosis, identified by nursing home staff participating in frontline LOCK sleep huddles as having sleep problems

You're excluded if

  • Residents with a high risk of OSA who are not being treated for OSA because actigraph measurements are inaccurate in that population.
  • Residents who have a persistent bilateral resting tremor or paralysis in both arms (a subset of persons with Parkinson's disease and related significant tremor-causing diagnoses), due to actigraph measurement inaccuracies

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2024-03-12

View full record on ClinicalTrials.gov

All APOE4 clinical trials