NCT05707663 · ACTIVE NOT RECRUITING
Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
This observational study is tracking brain development in young people who have Juvenile-onset Huntington's Disease, a rare form that appears before age 21. Researchers are using MRI, cognitive tests, and neurological exams to look for biomarkers that distinguish it from adult-onset Huntington's. No treatment is being tested — this is purely a research observation study, gathering data to better understand how the disease affects developing brains differently.
You may qualify if
- Clinical diagnosis of JoHD
- Aged 4-30
You're excluded if
- Metal in body
- History of head trauma, brain tumor, seizures or epilepsy unrelated to JoHD
- History of major surgery or serious chronic medical conditions other than JoHD
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-04-30