NCT05703386 · RECRUITING
Imaging the Pathogenesis of Cerebral Small Vessel Disease
This study is not testing a treatment. It is an observational study that uses repeated MRI scans to watch how white matter damage in the brain develops over time in people who already have small vessel disease and vascular risk factors like high blood pressure, high cholesterol, or diabetes. The goal is to better understand how this type of brain disease progresses, not to test whether anything slows or stops it.
You may qualify if
- Clinical or radiographic evidence of ischemic stroke
- One vascular risk factor (hypertension, hyperlipidemia, or diabetes)
- Evidence of cerebral small vessel disease on MRI
You're excluded if
- Inability to complete 3 research MRI scans over 1.25 years
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-03-03