NCT05591313 · COMPLETED
Acute Exercise on Neurocognitive Function Among Adults With/Without Generic Risk of AD
This trial tests whether a single bout of exercise at different intensities affects brain function in adults aged 50 to 70. The three conditions compare low-intensity exercise for 40 minutes, moderate-intensity for 30 minutes, and high-intensity for 16 minutes. Researchers also want to know whether APOE4 carrier status changes the response. This is a Phase NA behavioral study — it is exploratory research, not a drug or device being evaluated for approval.
You may qualify if
- Adults aged between 50 and 70 years old
- Normal or corrected-to-normal vision based on the minimal 20/20 standard
- Cognitively normal as mini-mental state examination scores (MMSE) > 26
You're excluded if
- Neurological or psychiatric disorders
- Cardiovascular disease
- Risk of cardiovascular fitness assessment based on the Physical Activity Readiness Questionnaire (PAR-Q)
- Red-green color blindness.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2023-02-08