NCT05574634 · RECRUITING
The Role of the Locus Coeruleus in Age-related Distractibility
This trial is studying a small brain region called the locus coeruleus and how its connections to attention networks may explain why older adults get more easily distracted. Participants will use a tablet-based cognitive training program to see whether improving those brain connections sharpens attention. This is a Phase NA study — meaning it is research-focused, exploring mechanisms rather than testing a treatment for approval.
Eligibility criteria
Inclusion: * Healthy adult participants * No younger than 18 and no older than 75 yrs of age * Ability to provide written informed consent Exclusion: * History of surgery involving metal implants * Possible metal fragments in the eyes * Pacemaker * A history of claustrophobia * Braces * Weighing over 250 pounds * Pregnant or possibility of being pregnant. * Severe medical or psychiatric conditions (e.g., blind or deaf, head trauma) * Learning disabilities or developmental disabilities
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-08-19