NCT05508841 · RECRUITING

Understanding How Alzheimer's Disease Impacts the Therapeutic Response to Transcranial Direct Current Stimulation

This trial is testing whether a higher dose of transcranial direct current stimulation (tDCS) — a non-invasive brain stimulation technique — combined with cognitive training improves thinking and memory in people with mild to moderate Alzheimer's. The standard dose used in most studies is 2 milliamps; this trial tests whether 4 milliamps produces stronger or more consistent results. This is a Phase NA study, meaning it is exploratory research rather than a late-stage efficacy trial.

You may qualify if

  • Mild to Moderate AD
  • Score between 18 and 25 on the MoCA
  • Able to do the N-Back task during the initial screening

You're excluded if

  • No history of stroke or TBI
  • No shunts or metal in the body
  • No history of significant heart disease, alcoholism and drug use

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2024-08-13

View full record on ClinicalTrials.gov

All APOE4 clinical trials