NCT05205980 · RECRUITING

Perturbation Training Reduces Falls in People With Alzheimer's Disease (AD)

This trial tests whether perturbation training — a physical therapy technique that uses sudden, controlled surface movements to teach the body how to recover from stumbles — can reduce falls in people already diagnosed with Alzheimer's disease. Researchers want to know if people with AD can learn and retain these balance-recovery skills. This is a Phase N/A study, meaning it is a practical intervention trial rather than a drug-approval study.

You may qualify if

  • Participants must be at least 65 years old;
  • Participants have a clinical diagnosis of probable AD;
  • Participants can read and understand English;
  • Participants must be able to walk independently at least 25 feet;
  • Participants must be able to stand independently for at least 30 seconds;
  • Participants must have a Montreal Cognitive Assessment score of 11-21 or Mini Mental Status Examination score between 18 and 23.

You're excluded if

  • Individuals have ever experienced perturbation training;
  • Individuals have hypotension or uncontrolled hypertension;
  • Individuals exhibit osteoporosis;
  • Participants suffer from coexisting psychiatric disorders, or other neurological conditions, or injuries, etc.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-02-04

View full record on ClinicalTrials.gov

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