NCT05068128 · ACTIVE NOT RECRUITING
Combined Flow and Pressure Study of Craniospinal Dynamic
This study is testing a new way to measure how cerebrospinal fluid and blood pressure interact inside the skull, using specialized MRI scans and a pressure infusion test. The goal is to build a better diagnostic model for normal pressure hydrocephalus, a condition where fluid buildup can cause dementia-like symptoms. The phase is unspecified, so this appears to be an exploratory or observational study rather than a standard drug or device trial.
Eligibility criteria
Inclusion Criteria: * age > 55 years * Patients with suspected active hydrocephalus (HA) known as "normal pressure": * Ventricular dilatation: Evans index > 0.3 * Patients with cognitive impairment, and/or gait disorders and/or urinary incontinence or a combination of these three symptoms. * Absence of other neurological diseases that could cause ventriculomegaly. * Information and collection of the patient's non opposition Exclusion Criteria: * All patients with neurological disease other than active hydrocephalus will be excluded. * Individuals who cannot tolerate an MRI examination * All individuals with implants, pacemakers, prostheses and ferromagnetic objects * Patients under guardianship, curators or safeguard of justice
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-04-10