NCT05020626 · RECRUITING
Modelling Tau Distribution From DTI With Generative Adversarial Network for Alzheimer's Disease Diagnosis
This is not a treatment trial. Researchers are training an AI model to generate synthetic tau-PET brain scans using a different, cheaper type of MRI called DTI. The goal is to see whether the AI-generated images can accurately estimate tau protein buildup in the brain without an actual PET scan. This is a diagnostic imaging research project with no specified phase — it tests a tool, not a therapy.
You may qualify if
- With the age of 55 years and above
- With brain MRI taken within ±6 months from the date of clinically confirmed diagnosis of AD, MCI or normal cognition.
You're excluded if
- AD with mixed dementia
- Non-AD dementia
- History of severe traumatic brain injury, severe depression, stroke, brain tumors, and incident major systemic illness
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-08-22