NCT04906863 · RECRUITING

Genetic Studies of Early-onset Dementia

This study collects blood samples, cognitive test results, and health questionnaires to find genetic factors linked to early-onset dementia — memory loss before age 70 — across different ethnic groups, including Alzheimer's disease and mild cognitive impairment. It is a genetic research study, not a treatment trial, so there is no drug or therapy being tested. Researchers are building a dataset to better understand who is at risk and why.

Eligibility criteria

Inclusion criteria:
* 18 years and older
* Individuals diagnosed with dementia, their family members and unrelated healthy controls without dementia.
Exclusion Criteria:
-Individuals with competing diagnosis such as Huntington's disease, traumatic brain injury, drug or alcohol abuse, or schizophrenia, etc., unless family members of a dementia affected individual

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2025-04-29

View full record on ClinicalTrials.gov

All APOE4 clinical trials