NCT04855630 · RECRUITING
Combating Alzheimer's Through Sleep and Exercise
This trial is testing whether a combination of structured exercise and monitored sleep — tracked with a DREEM 2 headband and a Fitbit — can affect dementia risk over time. Researchers will measure biomarkers and cognitive changes in people who already report some memory or concentration problems. This is a Phase NA study, meaning it is exploratory — gathering early data rather than proving a treatment works.
You may qualify if
- Able to perform mild exercise
- Able to wear DREEM 2 Headband
- Able to wear a Fitbit wrist watch
- Able to perform the Everlywell biomarker procedure
- Able to Understand and Speak English
- Able to operate a digital device like mobile phone, iPad, or computer
- Self-reported history of problems with cognitive impairment: memory, concentration, and processing information
- Only participants cognitively able and willing to provide consent will be included.
You're excluded if
- Prohibited from or unable to perform mild exercise
- Unable to wear wrist watch or headband devices, or unable to supply pinprick blood sample for any reason
- Unable to speak or understand English
- Unable to use mobile device/smartphone technology
- Unable or unwilling to consent for any reason.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-04-20