NCT03698747 · TERMINATED

Myelin Imaging in Concussed High School Football Players

This study uses a specialized MRI technique called McDESPOT to look at myelin — the protective coating around nerve fibers in the brain — in high school football players who have had a concussion. Researchers want to see whether a concussion changes myelin structure compared to teens who don't play contact sports. The phase is unspecified, so this appears to be observational research, not a treatment trial.

Eligibility criteria

Inclusion Criteria:
* Experimental Group
  * Patient age range: 9th through 12th grade (high school)
  * Male
  * Right-handed
  * Diagnosis of mTBI or concussion during a football game or training
  * No significant co-morbidities
  * Able to get an MRI
  * Potential subject must be capable of giving informed consent or assent when applicable
    • Control Group
  * Patient age range: 9th through 12th grade (high school)
  * Male Right-handed
  * Does not play contact sports (football, soccer, lacrosse)
  * No significant co-morbidities
  * Able to get an MRI
  * Potential subject must be capable of giving informed consent or assent when applicable
Exclusion Criteria:
* Unable to tolerate MRI scan

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2020-09-25

View full record on ClinicalTrials.gov

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