NCT01625195 · COMPLETED
Causal Relationships Between LC-omega-3-enriched Diet and Cognition
This trial is testing whether a diet enriched with long-chain omega-3 fatty acids improves cognition in adults aged 20 to 80. Researchers are measuring effects on memory, verbal fluency, and visuospatial skills in a randomized, double-blind, placebo-controlled design — meaning neither participants nor researchers know who gets the real supplement. This is a Phase NA study, meaning it is a nutritional investigation rather than a standard drug trial phase.
You may qualify if
- male and female subjects aged between 20-80 years old
You're excluded if
- tobacco use,
- malnutrition (assessed from blood albumin, hemoglobin and lipids),
- subjects taking an EPA+DHA supplement for more than one month,
- swallowing problems,
- severe gastro-intestinal problems,
- diabetes,
- uncontrolled thyroid disease,
- severe renal failure,
- liver disease or any other endocrine disorder,
- medication that would affect lipoprotein metabolism,
- chronic immune condition or inflammation (CRP > 10 mg/l, white cell count),
- cancer,
- recent major surgery or cardiac event,
- pregnant or lactating women,
- uncorrected visual or hearing problems,
- dementia,
- ongoing or past severe drug or alcohol abuse,
- psychiatric difficulties or depression, and
- ongoing or past intensive physical training
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2020-05-08